![]() ![]() ![]() Ibuprofen comes alone and in combination with other medications. Do not take more or less of it or take it more often than directed by the package label or prescribed by your doctor. Follow the directions on the package or prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. If you are taking ibuprofen on a regular basis, you should take it at the same time(s) every day. Ibuprofen may be taken with food or milk to prevent stomach upset. Children and infants may usually be given nonprescription ibuprofen every 6 to 8 hours as needed for pain or fever, but should not be given more than 4 doses in 24 hours. Adults and children older than 12 years of age may usually take nonprescription ibuprofen every 4 to 6 hours as needed for pain or fever, but should not take more than 6 doses in 24 hours. Nonprescription ibuprofen comes as a tablet, chewable tablet, capsule, gel capsule, suspension (liquid), and drops (concentrated liquid). It is usually taken three or four times a day for arthritis or every 4 to 6 hours as needed for pain. Prescription ibuprofen comes as a tablet and suspension (liquid) to take by mouth. You can also visit the Food and Drug Administration (FDA) website ( ) or the manufacturer's website to obtain the Medication Guide. Read the information carefully and ask your doctor or pharmacist if you have any questions. Your doctor or pharmacist will give you the manufacturer's patient information sheet (Medication Guide) when you begin treatment with prescription ibuprofen and each time you refill your prescription. Be sure to tell your doctor how you are feeling so that your doctor can prescribe the right amount of medication to treat your condition with the lowest risk of serious side effects. Your doctor will monitor your symptoms carefully and will probably order certain tests to check your body's response to ibuprofen. Keep all appointments with your doctor and the laboratory. If you experience any of the following symptoms, stop taking ibuprofen and call your doctor: stomach pain, heartburn, vomit that is bloody or looks like coffee grounds, blood in the stool, or black and tarry stools. Also tell your doctor if you have or have ever had ulcers, bleeding in your stomach or intestines, or other bleeding disorders. Tell your doctor if you take any of the following medications: anticoagulants ('blood thinners') aspirin other NSAIDs such as naproxen (Aleve, Naprosyn) oral steroids such as dexamethasone, methylprednisolone (Medrol), and prednisone (Rayos) selective serotonin reuptake inhibitors (SSRIs) such as citalopram (Celexa), fluoxetine (Prozac, Sarafem, Selfemra, in Symbyax), fluvoxamine (Luvox), paroxetine (Brisdelle, Paxil, Pexeva), and sertraline (Zoloft) or serotonin norepinephrine reuptake inhibitors (SNRIs) such as desvenlafaxine (Khedezla, Pristiq), duloxetine (Cymbalta), and venlafaxine (Effexor XR). The risk may be higher for people who take NSAIDs for a long time, are older in age, have poor health, who smoke, or who drink large amounts of alcohol while taking ibuprofen. These problems may develop at any time during treatment, may happen without warning symptoms, and may cause death. NSAIDs such as ibuprofen may cause ulcers, bleeding, or holes in the esophagus (tube between the mouth and stomach), stomach, or intestine. If you will be undergoing a coronary artery bypass graft (CABG a type of heart surgery), you should not take ibuprofen right before or right after the surgery. Get emergency medical help right away if you experience any of the following symptoms: chest pain, shortness of breath, weakness in one part or side of the body, or slurred speech. Tell your doctor if you or anyone in your family has or has ever had heart disease, a heart attack, or a stroke if you smoke and if you have or have ever had high cholesterol, high blood pressure, or diabetes. Do not take an NSAID such as ibuprofen if you have recently had a heart attack, unless directed to do so by your doctor. These problems may develop at any time during treatment, but the risk may be higher for people who take NSAIDs for a long time or at higher doses. These events may happen without warning and may cause death. People who take nonsteroidal anti-inflammatory drugs (NSAIDs) (other than aspirin) such as ibuprofen may have a higher risk of having a heart attack or a stroke than people who do not take these medications. ![]()
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